About

Creating biologics of the future

Biologic therapeutics have transformed medicine in the past 40 years. They’ve enabled treatments for some of the most challenging diseases. However, today’s biologic medicines use conventional building blocks that the human body is designed to recognize and break down. Further, they are difficult to modify or conjugate, all of which limits their therapeutic potential.

We asked, “What if we could design biologics entirely with new building blocks that could overcome the most critical limitations of today’s medicines?”

At Abiologics, we are leveraging a variety of computational design tools to create protein-inspired molecules that exist in a class of their own – Synteins™. While Synteins™ reflect protein structures from nature, their computational conception and chemical creation permit nearly infinite degrees of freedom to craft the ideal molecule for each unique task. They are free from the inherent weaknesses and vulnerabilities that limit natural proteins’ potential as medicines, and are designed to have extraordinary properties and expanded functions to offer key benefits to patients.

Team

Avak Kahvejian
Co-Founder and Chief Executive Officer
General Partner, Flagship Pioneering
Maria-Chiara Magnone
Chief Scientific Officer
Mike Hamill
Chief Innovation Officer
Senior Principal, Flagship Pioneering
Kala Subramanian
President
Operating Partner, Flagship Pioneering
Jaclyn Dunphy
Senior Director, Strategy and Research Operations
Daniel Smith
Senior Director, Head of Computation
Xin Sun
Director, Head of Discovery
Noubar Afeyan
Co-Founder and Chairman of Strategic Oversight Board
Founder and Chief Executive Officer, Flagship Pioneering
Avak Kahvejian
Co-Founder and Chief Executive Officer
General Partner, Flagship Pioneering
Mike Hamill
Chief Innovation Officer
Senior Principal, Flagship Pioneering
Kala Subramanian
President
Operating Partner, Flagship Pioneering
Jaclyn Dunphy
Senior Director, Strategy and Research Operations
Alicia Kaestli
Senior Associate, Flagship Pioneering
Brad Pentelute
Academic Co-Founder, Abiologics
Professor of Chemistry, MIT
Gevorg Grigoryan
Co-Founder and Chief Technology Officer, Generate:Biomedicines
Tony Manning
Former CSO, Momenta Pharmaceuticals
Cristina Rondinone
Founder and CEO, Pep2Tango Therapeutics
Tomi Sawyer
President, Maestro Therapeutics
Melissa Starovasnik
Former VP Protein Sciences, Genentech

Join our team

If you’re interested in joining our team of creative scientist-entrepreneurs to develop extraordinary therapeutics with the potential for broad patient impact, connect with us.

Careers